Home Clinical Trials Indian Covaxin Immunization Alone Cannot Be Enough To Defeat Covid-19 Pandemic: Round The Globe

Indian Covaxin Immunization Alone Cannot Be Enough To Defeat Covid-19 Pandemic: Round The Globe

by Medical Director
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Even with Covid immunization efforts in full force, the hypothetical brink for conquering COVID-19 looks to be out of scope. With COVID-19 injections rolling out athwart many nations, the world’s largest philanthropical network is once again threatening that vaccines alone will not culminate the pandemic. Individuals need to endure attentive and continue to follow the basic anticipatory events that embrace of physical distancing, wearing n95 masks and hand-washing. CoVID-19 continues to kill thousands of people every day. Patience is key and loyalty is essential. The ability to be healthy and safe is literally in our hands. It is our responsibility to take precautionary measures to ensure that everyone is vigilant and prevents its spread.

Yes, it will take months for everyone to get vaccinated. Yes, there are gaps in the Govt administration’s plan to provide vaccines, including promising medications that are not available. There seems to be a light at the end of the tunnel. If we maintain a social space, wear masks and wash our hands, many feels that we prevent/hold Covid before we get vaccinated.

Mass immunization is essential. But herd immunity is a different game. This is defined as the time when the community spread of Covid stops, as unprotected people are surrounded by “herd” of individual who are immune to infections, which makes it difficult to transmit the disease, even if it is impossible to infected individuals.

The principle of herd immunity has other obstacles. Getting vaccinated – as how many people have been vaccinated – is much less than what we need because Covid 19 believes it is politicized around the world and not a single percent of the population thinks the disease is real.

With the exception of those outside the SARS-COV-2 vaccination due to age or other conditions, 81% of Americans do not have a vaccination restriction. Including 19 percent Americans who don’t really want the vaccine and 23 percent who will only get it when they need it, in the near future only 54 percent Americans will have immunity. If half the individuals are waiting and don’t get vaccinated (still 12% of the population), we see only 35% of vaccines with less than 65% herd immunity. It remains to be seen whether the effectiveness of good vaccines will be lower than the level of clinical trials. We still don’t know the immune response against various vaccines. It may still continue. Or they can go away, remain vulnerable after vaccination, and create new disease conditions.

We also need to monitor for vaccines to find out what is needed for immune system resistance and stimulation, such as tetanus and diphtheria. Eventually, it seems that soon the public health infrastructure of our country will be strengthened, new protocols for controlling new viruses will be created.

It’s time to stop promoting the bigotry belief that the unrealistic goal of herd immunity can be achieved in 2022 and start looking to reinforcing all aspects of the health care response as we start to concede that Covid-19 will become an endemic disease that will continue to lurk in the population. For the foreseeable future, that means continued physical distancing; occupancy limits in restaurants and other retail establishments; replacement of physical menus with smart phone-based menus to prevent surface spread of the virus, and more.

Vaccines will help us, but if we don’t pay full attention and the immunization is properly and immediately accelerated around the world, everyone is still in danger. Asymptomatic and pre-symptomatic transfers are a challenge for public health and an unprecedented rate of infection. Without extensive control and epidemiological measures to prevent fires from burning, COVID-19 pandemic cannot be completely eradicated.

STILL UNCERTAIN WHETHER IMMUNIZATION BLOCK TRANSMISSION

The key to herd immunity is that even if the individual is infected, there are very few vulnerable hosts that can survive – people who have been vaccinated or are already infected are less likely to spread the virus. For example, Covid-19 vaccines are very effective in preventing symptomatic disease, but it is not yet clear whether they prevent the disease or spread it to others. This creates a problem for the herd immunity.

IRREGULAR VACCINE ROLL-OUT

In many countries, the vaccine is divided according to age priority and older people are at higher risk of dying from COVID-19. It remains to be seen when and whether the childhood vaccine will be approved. Even for a country with a high vaccination rate, if the surrounding countries haven’t done the same and the population can intervene, there is still the possibility of a new entry of covid virus.

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NEW MUTATION VARIANTS ALTER THE HERD-IMMUNITY EQUATION

Vaccine allocation and distribution should be addressed in new SARS-COV-2 swamps, which may be more sensitive and resistant to vaccines. We compete for new mutation variants. The longer it takes for the virus to vaccinate, the longer it takes for this type of virus to appear and spread. High levels of immunity can cause selective pressure and can lead to disease in people with immunity. Quick and complete immunization can prevent from new variant. But, again, the imbalanced immunization creates a big challenge.

SHORT DURATION IMMUNITY

The calculation of herd immunity takes into account two individual sources of immunity: vaccines and natural infections. People infected with SARS-COV-2 have some degree of immunity to the virus, but its duration is questionable. If the immunity based on the infection lasts for a few months, the vaccination period is fixed. It will also determine how long the vaccine immunity will last and whether it should be bolstered over time. For both of these reasons, COVID-19 can cause the flu.

IMMUNIZATION MIGHT TRANSFORM HUMAN BEHAVIOUR

With the current vaccination rate, the world is approaching theoretical barriers to herd immunity. The problem is, the more people are immunized, the more they interact with individuals, which changes the equation of herd immunity, which is partly based on the appearance of the Covid virus. The vaccine is not bulletproof. Imagine that the vaccine offers 90 percent protections: “If you met at least one person before you got vaccinated, but now you get vaccinated with ten people, you are back to square one.

Even with no herd immunity, the ability to vaccinate vulnerable people appears to reduce hospitalization and mortality as a result of COVID-19. The disease may not go away quickly, but the chances may drop.

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